Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00072Alirocumab--
BADD_D00073Aliskiren0.004189%
BADD_D00074Aliskiren hemifumarate--
BADD_D00076Allopurinol--
BADD_D00082Alosetron--
BADD_D00084Alpha-1-proteinase inhibitor (human)--
BADD_D00085Alprazolam--
BADD_D00086Alprostadil--
BADD_D00100Ambrisentan0.059178%
BADD_D00103Amikacin0.010026%
BADD_D00105Amiloride hydrochloride--
BADD_D00115Amiodarone0.054763%
BADD_D00116Amiodarone hydrochloride--
BADD_D00121Amlodipine0.000292%
BADD_D00122Amlodipine besylate--
BADD_D00129Amoxicillin--
BADD_D00132Amphotericin b0.000824%
BADD_D00139Anagrelide--
BADD_D00140Anagrelide hydrochloride--
BADD_D00142Anastrozole0.004148%
BADD_D00143Anidulafungin--
BADD_D00146Anti-thymocyte globulin (rabbit)--
BADD_D00147Antihemophilic factor (recombinant)--
BADD_D00150Antivenin (micrurus fulvius)--
BADD_D00151Apixaban--
BADD_D00152Apomorphine--
BADD_D00156Apremilast0.259388%
BADD_D00157Aprepitant--
BADD_D00158Aprotinin (bovine)--
BADD_D00161Argatroban--
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